One important feature of cancer is the rapid division and growth of cancer cells, and this process requires a lot of energy as a support, the British researchers recently published report that they found a way to limit the method of cell energy source, available in this way "starve" cancer cells to help treat cancer.
UK researchers from Imperial College and other institutions in the new issue of "Nature Cell Biology" magazine reported that cancer cells often rely on decomposition of glucose to obtain energy, if the body's glucose levels less than other energy source is turned, the researchers found called NF-kB proteins that control the conversion of its energy supply means, if the inhibition of the function of this protein, cancer cells can not convert the energy supply-demand approach, the energy supply will enter the state or even "starve to death."
The researchers used colon cancer cells in laboratory experiments showed that this restriction can be a way to supply energy to kill cancer cells. In addition, if the protein in the inhibition of NF-kB function at the same time, using an existing diabetes drug metformin, the "starve" the cancer cells will greatly enhance efficiency.
led the research, Professor, this is the first to reveal the protein NF-kB can regulate the function of cellular energy source, although aware of it before playing a role in cancer, but the exact mechanism is not very clear , the associated effects of cancer treatment is not very satisfactory. The study also found that it can be and metformin combination is expected on this basis to develop more effective cancer treatment.
2011年10月16日星期日
Hypertension medication reminder
1, when the drug treatment
Many people think that high blood pressure medicine one can not stop eating, so can not just eat as much as possible to lower blood pressure through lifestyle. TAN Ning said, controlling blood pressure is certainly needed lifestyle changes, but has no medication, only for the early development of hypertension, atherosclerosis and heart checked no hypertrophy of people. Early detection of high blood pressure in 3-6 months, to allow them to make lifestyle changes to lower blood pressure. If after the blood pressure down, you can continue to observe, not medicine. But did not fall down, we must adhere to medication.
2, the medication should be individualized
Many doctors feel that patients with hypertension trouble, see other people with good medicine, according to someone else's prescription to eat. Experts say there are four types of commonly used hypertension drugs, each with advantages and disadvantages, patients should be selected according to their medication status, in order to achieve good results.
① blood pressure lowering drugs have some impact on sexual function in young patients should use angiotensin system inhibitors, the least impact on sexual function.
② Some people function well, should use diuretics, angiotensin system inhibitors may enhance the antihypertensive effect.
③ high systolic blood pressure tend to mainly elderly, and systolic blood pressure-lowering effect of calcium antagonists best.
3, emphasizing the combination therapy
Antihypertensive drugs not eat one, then eat two. Some patients to eat a single drug doubled, so very safe. In comparison, the combination therapy is better, less side effects
Many people think that high blood pressure medicine one can not stop eating, so can not just eat as much as possible to lower blood pressure through lifestyle. TAN Ning said, controlling blood pressure is certainly needed lifestyle changes, but has no medication, only for the early development of hypertension, atherosclerosis and heart checked no hypertrophy of people. Early detection of high blood pressure in 3-6 months, to allow them to make lifestyle changes to lower blood pressure. If after the blood pressure down, you can continue to observe, not medicine. But did not fall down, we must adhere to medication.
2, the medication should be individualized
Many doctors feel that patients with hypertension trouble, see other people with good medicine, according to someone else's prescription to eat. Experts say there are four types of commonly used hypertension drugs, each with advantages and disadvantages, patients should be selected according to their medication status, in order to achieve good results.
① blood pressure lowering drugs have some impact on sexual function in young patients should use angiotensin system inhibitors, the least impact on sexual function.
② Some people function well, should use diuretics, angiotensin system inhibitors may enhance the antihypertensive effect.
③ high systolic blood pressure tend to mainly elderly, and systolic blood pressure-lowering effect of calcium antagonists best.
3, emphasizing the combination therapy
Antihypertensive drugs not eat one, then eat two. Some patients to eat a single drug doubled, so very safe. In comparison, the combination therapy is better, less side effects
2011年10月8日星期六
20 simple diet habits
1, give yourself read a "do not eat anything after 9:00," the spell, which means that dinner can not be postponed until after 9 or after 9 also get unhealthy food to Tiandu Zi. Arrangements for your last meal time meals and snacks, just before going to bed so that the body digest the food.
2, eating before drinking a glass of protein smoothie snow (a milk + fruit juice, protein powder can be added into the "Protein Smoothie Snow"). Snow may be yearning protein taste does not taste good, but it allows you to eat for some time, so you do not point a lot of dishes.
3, time out, the car stopped at a place farther away, walking a little more exercise. If you used to go out with a backpack, so much the better, exercise even more.
4, put his day off. Friday is usually the best, because a week has passed, anyone need a break. You can not restrain myself to eat some of the usual eat, of course, should not be too obsessed.
5, the weekend should exercise. Most people can find a lot of reasons for not exercising the weekend, but if you are willing to spend some time on weekends to exercise, you will achieve your weight loss goals faster.
6, if you bother to open the stove to cook something, you use the microwave it. Make their own nutritious diet breakfast: eggs, vegetables, low-fat cheese.
7, imagine your stomach into a ball of fire, if you continue to add fuel to it, it will always burn, fire is very intense. Similarly, the campaign, this group of fire will burn more vigorous, you throw anything, will burn even more accelerated.
8, the weekend before the carnival do first movement. So that when you eat, drink at night and they will think twice after eating it!
9, do not put salad dressing into the salad, but on the side, coated with salad dressing to go with a fork salad fork. In this way, you can taste the delicious sauce, but do not put too much lead.
10, often climbing stairs. My office on the 11th floor and 11th floor to the basement from the 368 stairs (I counted). If I run twice a day, on my weight loss goals from far away.
11, do not use high-calorie sauce to taste, often see health magazine, learn to lose weight dishes.
12, tell the world your weight loss goals, so that the world will inspire you to lose weight to power.
13, to find a weight loss partner. If you always encourage your partner to achieve their goals, your partner will encourage you to work together.
14, design a weight loss progress of the spreadsheet, then print out attached to the office where everyone can see, or at home on the wall.
15, the most beautiful body, when you put a photo of the vanity mirror in the bedroom, so you can see it first thing the morning. Or buy a must to lose weight before you wear nice clothes every day to try and see how you progress.
16, put a healthy and nutritious snacks in your briefcase, is one kind of weight. When you work overtime, this can eat a snack so that they are not too hungry, but not too full, because even after a good meal.
17, pre-dinner drink a glass of water every 18 to a box of instant oatmeal or whole wheat crackers as a snack on the desk. Do not do something right, like my colleagues to eat candy.
19, if you do not buy junk food home, so you will not want to eat the. Before buying every kind of food, to seriously look at the nutrition label. If you particularly like to eat fast food, you can visit the restaurant website, see if you can find the fat and calorie content of food.
20. Carry a rope. Especially when working long hours, out 5-10 minutes of time to jump rope. This will help you during working hours in the exercise, lose weight. Meals are.
2, eating before drinking a glass of protein smoothie snow (a milk + fruit juice, protein powder can be added into the "Protein Smoothie Snow"). Snow may be yearning protein taste does not taste good, but it allows you to eat for some time, so you do not point a lot of dishes.
3, time out, the car stopped at a place farther away, walking a little more exercise. If you used to go out with a backpack, so much the better, exercise even more.
4, put his day off. Friday is usually the best, because a week has passed, anyone need a break. You can not restrain myself to eat some of the usual eat, of course, should not be too obsessed.
5, the weekend should exercise. Most people can find a lot of reasons for not exercising the weekend, but if you are willing to spend some time on weekends to exercise, you will achieve your weight loss goals faster.
6, if you bother to open the stove to cook something, you use the microwave it. Make their own nutritious diet breakfast: eggs, vegetables, low-fat cheese.
7, imagine your stomach into a ball of fire, if you continue to add fuel to it, it will always burn, fire is very intense. Similarly, the campaign, this group of fire will burn more vigorous, you throw anything, will burn even more accelerated.
8, the weekend before the carnival do first movement. So that when you eat, drink at night and they will think twice after eating it!
9, do not put salad dressing into the salad, but on the side, coated with salad dressing to go with a fork salad fork. In this way, you can taste the delicious sauce, but do not put too much lead.
10, often climbing stairs. My office on the 11th floor and 11th floor to the basement from the 368 stairs (I counted). If I run twice a day, on my weight loss goals from far away.
11, do not use high-calorie sauce to taste, often see health magazine, learn to lose weight dishes.
12, tell the world your weight loss goals, so that the world will inspire you to lose weight to power.
13, to find a weight loss partner. If you always encourage your partner to achieve their goals, your partner will encourage you to work together.
14, design a weight loss progress of the spreadsheet, then print out attached to the office where everyone can see, or at home on the wall.
15, the most beautiful body, when you put a photo of the vanity mirror in the bedroom, so you can see it first thing the morning. Or buy a must to lose weight before you wear nice clothes every day to try and see how you progress.
16, put a healthy and nutritious snacks in your briefcase, is one kind of weight. When you work overtime, this can eat a snack so that they are not too hungry, but not too full, because even after a good meal.
17, pre-dinner drink a glass of water every 18 to a box of instant oatmeal or whole wheat crackers as a snack on the desk. Do not do something right, like my colleagues to eat candy.
19, if you do not buy junk food home, so you will not want to eat the. Before buying every kind of food, to seriously look at the nutrition label. If you particularly like to eat fast food, you can visit the restaurant website, see if you can find the fat and calorie content of food.
20. Carry a rope. Especially when working long hours, out 5-10 minutes of time to jump rope. This will help you during working hours in the exercise, lose weight. Meals are.
2011年7月16日星期六
Murdoch lieutenant Hinton quits Dow Jones
NEW YORK (Reuters) - Les Hinton, the top executive of Rupert Murdoch's Dow Jones & Co, resigned on Friday after becoming a target of criticism for the phone-hacking scandal that occurred when he oversaw News Corp's British newspapers.
Hinton stepped down as the British phone hacking scandal surrounding News Corp began to spread to the United States. He is the highest ranking executive yet to resign over a crisis that closed down the News of the World tabloid and scotched News Corp's $12 billion attempt to buy out BSkyB.
"I have watched with sorrow from New York as the News of the World story has unfolded," Hinton wrote in a memo to staff after resigning as chief executive of Dow Jones and publisher of The Wall Street Journal.
"That I was ignorant of what apparently happened is irrelevant and in the circumstances I feel it is proper for me to resign from News Corp, and apologize to those hurt by the actions of the News of the World," he added.
At the Wall Street Journal, news of Hinton's departure was greeted by gasps and a stunned silence, despite much speculation in both London and New York that he could be toppled by transgressions that occurred on his watch.
Hinton's resignation came on the same day that another top Murdoch confidante, Rebekah Brooks, stepped down as chief of News International, which is responsible for all Murdoch's British papers. Brooks worked under Hinton when she was News of the World's editor and he ran News International.
News Corp is attempting to quiet the storm surrounding revelations of telephone hacking at News of the World. The resignations follow News Corp's decision to abandon a $12 billion plan to buy full control of pay TV operator BSkyB.
A person close to the company described Hinton as "the ultimate company man" who had come to the conclusion that someone had to take full responsibility for the hacking that occurred under his watch.
The decision was made over the past few days, following back-and-forth discussions with Murdoch, the person said, adding that the final say came down to Hinton.
"Les saw the hurt that was happening with the company and wanted to ameliorate the situation," the person said.
Hinton, 67, has worked alongside Murdoch for more than five decades, rising through the ranks until he was tapped to run News International in 1995, and later Dow Jones after News Corp bought the publisher of the Wall Street Journal.
On two occasions starting in 2007, Hinton addressed British parliamentary committees about the News of the World phone hacking, testifying both times that a full internal investigation had been carried out.
That testimony has resurfaced in press reports over recent days as new questions have been made about the depth of phone hacking at the tabloid -- including allegations that victims of notorious crimes, bombings and war may have been targeted.
There has been a lot of pressure on Murdoch to sell off his newspapers since the scandal broke, something he has resisted so far. Murdoch did, however, shut down News of the World on Sunday, and his sacrifice of Hinton and Brooks now was seen as a reflection of the depth of the crisis rocking News Corp.
"Les fell on his sword for Murdoch," said Jeff Jarvis, a journalism professor at City University of New York who had worked for Hinton when News Corp owned TV Guide.
"Murdoch isn't loyal to media assets but he's very loyal to those that are loyal to him," Jarvis added.
In a memo to Dow Jones' staff Murdoch said he accepted Hinton's resignation with the "heaviest of hearts," but the 80-year-old media power also attempted to deflect some of the wider criticism of the company.
"Let me emphasize one point - News Corporation is not Rupert Murdoch. It is the collective creativity and effort of many thousands of people around the world," he said.
In a memo to Wall Street Journal staff, editor Robert Thomsoncredited Hinton with transforming Dow Jones and avoiding hundreds of editorial layoffs when the company was "at the mercy of management consultants."
"In the most turbulent of times for 'old' media, Les steered us back into profitability and made us a digital force around the world," said Thomson.
News Corp is not seeking a replacement for Hinton at present, the person close to the company said.
Dow Jones President Todd Larsen, a former Booz Allen consultant, will report to News Corp Chief Operating Officer Chase Carey, the company said.
Reuters is a competitor of Dow Jones Newswires, the financial news agency that News Corp acquired along with the Wall Street Journal in 2007.
(Reporting by Paul Thomasch and Yinka Adegoke; editing Carol Bishopric)
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